Amlodipine vs Semintra: what's the difference?
How Amlodipine and Semintra compare: what each is for, how it works, side effects and cost, side by side.
Last updated: October 2026 · 2 sources · see sources
Side by side
| Amlodipine | Semintra | |
|---|---|---|
| Generic name | Amlodipine | Telmisartan |
| Brand names | Norvasc | Semintra |
| For | Dogs and cats | Dogs and cats |
| Prescription | Prescription | Prescription |
| Used for | Treats high blood pressure, especially in cats, to protect the kidneys, eyes and brain. [1] | Treats high blood pressure in cats and protein loss in the urine with kidney disease. [2] |
| How it works | A calcium-channel blocker that relaxes blood vessels. [1] | An angiotensin receptor blocker that relaxes blood vessels and protects the kidney filters. [2] |
| Common side effects | Cats: vomiting, diarrhea, low appetite, sleepiness. Dogs: gum overgrowth. [1] | Vomiting, diarrhea, low appetite, low blood pressure and low energy. [2] |
| Use with care | Not for pets in shock or with liver failure or aortic stenosis. Your vet will recheck blood pressure. [1] | Not for dehydrated or pregnant pets or pets with low blood pressure. [2] |
| Full guide | Amlodipine guide | Semintra guide |
Key differences
- They belong to different medicine groups on our site: Amlodipine: heart & blood pressure; Semintra: urinary & kidney.
Which one is right for my pet?
That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.
Switching from Amlodipine to Semintra is common, but do it only with your vet's plan.
Common questions
What is the difference between Amlodipine and Semintra?
Both treat high blood pressure in cats. Amlodipine is a calcium-channel blocker; Semintra is an angiotensin receptor blocker.
Is Amlodipine better than Semintra?
Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.
Can my pet take Amlodipine and Semintra together?
Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.
Do Amlodipine and Semintra need a prescription?
Amlodipine: Yes. It needs a prescription from a veterinarian. Semintra: Yes. It needs a prescription from a veterinarian.
Related
This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.