Bravecto vs Credelio: what's the difference?
How Bravecto and Credelio compare: what each is for, how it works, side effects and cost, side by side.
Last updated: October 2026 · 2 sources · see sources
Side by side
| Bravecto | Credelio | |
|---|---|---|
| Generic name | Fluralaner | Lotilaner |
| Brand names | Bravecto, Bravecto Plus | Credelio, Credelio Cat, Credelio Quattro |
| For | Dogs and cats | Dogs and cats |
| Prescription | Prescription | Prescription |
| Used for | Kills fleas and ticks for up to 12 weeks in dogs and cats. Sometimes used for mange and ear mites. [1] | Kills fleas and treats and controls several kinds of ticks in dogs and cats. [2] |
| How it works | After it is given, it spreads through the body. Fleas and ticks are exposed when they bite and are killed. [1] | Absorbed into the body; fleas and ticks die after biting. [2] |
| Common side effects | Vomiting, diarrhea, low appetite and flaky skin. [1] | Vomiting, diarrhea, low appetite and flaky skin. [2] |
| Use with care | It belongs to the isoxazoline class, which the FDA says has been linked to tremors, wobbliness and seizures in some pets. Tell your vet if your pet has ever had a seizure. [1] | An isoxazoline, so use caution in pets with seizures. Not for kittens under 8 weeks. [2] |
| Full guide | Bravecto guide | Credelio guide |
Key differences
On the basics they are alike: same kind of animal, same way to get them. The differences are in how they work and what else they cover, shown in the table above.
Which one is right for my pet?
That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.
Switching from Bravecto to Credelio is common, but do it only with your vet's plan.
Common questions
What is the difference between Bravecto and Credelio?
Both kill fleas and ticks in dogs and cats. Bravecto lasts up to 12 weeks per dose.
Is Bravecto better than Credelio?
Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.
Can my pet take Bravecto and Credelio together?
Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.
Do Bravecto and Credelio need a prescription?
Bravecto: Yes. It needs a prescription from a veterinarian. Credelio: Yes. It needs a prescription from a veterinarian.
Related
This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.