Medication comparison

Convenia vs Clavamox: what's the difference?

How Convenia and Clavamox compare: what each is for, how it works, side effects and cost, side by side.

Last updated: October 2026 · 2 sources · see sources

Quick answerConvenia is one long-acting antibiotic shot at the clinic, handy when pills are hard to give; Clavamox is given by mouth at home. [1][2]

Side by side

Convenia vs Clavamox compared
ConveniaClavamox
Generic nameCefovecinAmoxicillin-clavulanate
Brand namesConveniaClavamox
ForDogs and catsDogs and cats
PrescriptionPrescription, given at the clinicPrescription
Used forA long-acting antibiotic shot for skin infections, dental disease and urinary infections. Useful when pills are hard to give. [1]Treats skin and soft tissue infections, gum disease in dogs and urinary infections in cats. [2]
How it worksA cephalosporin given as one injection. The body clears it very slowly, so a single shot keeps working for a long time. [1]Amoxicillin kills bacteria by damaging their cell walls. Clavulanate protects the amoxicillin from enzymes some bacteria use to fight back. [2]
Common side effectsSluggishness, low appetite, vomiting, diarrhea and skin reactions at the injection site. [1]Stomach upset, vomiting and diarrhea. Giving it with food can help. [2]
Use with careNot for pets allergic to penicillins or cephalosporins, or for rabbits and guinea pigs. Because it lasts so long, a reaction can't be quickly reversed. [1]Not for pets allergic to penicillins or cephalosporins. Finish the full course even if your pet seems better. [2]
Full guideConvenia guideClavamox guide

Key differences

Which one is right for my pet?

That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.

Switching from Convenia to Clavamox is common, but do it only with your vet's plan.

About dosesWe don't list doses. The right amount depends on your pet's weight, health and other medicines, and only your vet can set it.

Common questions

What is the difference between Convenia and Clavamox?

Convenia is one long-acting antibiotic shot at the clinic, handy when pills are hard to give; Clavamox is given by mouth at home.

Is Convenia better than Clavamox?

Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.

Can my pet take Convenia and Clavamox together?

Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.

Do Convenia and Clavamox need a prescription?

Convenia: Yes. It's prescription-only and is usually given at the vet clinic. Clavamox: Yes. It needs a prescription from a veterinarian.

This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Cefovecin (veterinary drug handout)
  2. VCA Animal Hospitals – Amoxicillin-clavulanate (veterinary drug handout)