Cushing's disease in dogs
Cushing's disease (hyperadrenocorticism) means the body makes too much cortisol. Most cases come from a small pituitary tumor; some come from an adrenal tumor.
Last updated: October 2026 · 2 sources · see sources
Signs to watch for
- Drinking and peeing a lot
- Big appetite
- Pot-bellied look
- Thin skin and hair loss
- Panting
Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.
How vets diagnose it
Bloodwork and a urine test come first. An ACTH stimulation test or low-dose dexamethasone suppression test confirms it, and an abdominal ultrasound checks the adrenal glands. [2]
How it's treated
Most dogs take daily medicine (usually trilostane) with regular blood tests to adjust it. Adrenal tumors may be removed surgically. [2]
Medicines your vet may mention: Vetoryl. We don't list doses; your vet will decide what fits your pet.
What it costs to diagnose and manage
| Item | Typical US price | Src |
|---|---|---|
| Diagnosis (exam and tests) | $500–$1,500 | [1] |
| Ongoing treatment, per month | $50–$200 | [1] |
| First-year total | $2,000–$5,000 | [1] |
| Each year after that | $1,500–$4,000 | [1] |
These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.
Outlook
With treatment and monitoring, many dogs feel much better and live comfortably for years. [2]
Common questions
What is Cushing's disease in dogs?
Cushing's disease (hyperadrenocorticism) means the body makes too much cortisol. Most cases come from a small pituitary tumor; some come from an adrenal tumor.
What are the signs of Cushing's disease?
Common signs include: drinking and peeing a lot, big appetite, pot-bellied look, thin skin and hair loss, panting.
How do vets diagnose Cushing's disease?
Bloodwork and a urine test come first. An ACTH stimulation test or low-dose dexamethasone suppression test confirms it, and an abdominal ultrasound checks the adrenal glands.
How is Cushing's disease treated?
Most dogs take daily medicine (usually trilostane) with regular blood tests to adjust it. Adrenal tumors may be removed surgically.
How much does Cushing's disease cost to treat?
Diagnosis (exam and tests): $500–$1,500; Ongoing treatment, per month: $50–$200; First-year total: $2,000–$5,000; Each year after that: $1,500–$4,000. Costs vary with severity, tests, your pet's size and where you live.
Related
This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.