Lymphoma in dogs
Lymphoma is a cancer of the lymphocytes, a type of white blood cell. It's one of the most common cancers in dogs.
Last updated: October 2026 · 3 sources · see sources
Signs to watch for
- Firm, swollen lymph nodes under the jaw, in front of the shoulders or behind the knees
- Low energy
- Weight loss
- Drinking more
Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.
How vets diagnose it
A needle sample of a lymph node usually diagnoses it. Bloodwork, X-rays, ultrasound and special lab tests help with staging. [3]
How it's treated
Chemotherapy is the main treatment, and most dogs handle it much better than people do. Prednisone alone is a comfort-focused option. [3]
Medicines your vet may mention: Prednisone & Prednisolone, Chlorambucil (Leukeran). We don't list doses; your vet will decide what fits your pet.
What it costs to diagnose and manage
| Item | Typical US price | Src |
|---|---|---|
| Diagnosis (exam and tests) | $500–$1,000 | [1] |
| Treatment | $3,000–$10,000 | [1] |
| Lymphoma chemotherapy, dog (CareCredit) | $5,254 | [2] |
These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.
Outlook
Chemo often brings remission for months, but lymphoma usually returns. Your oncologist will talk through realistic goals. [3]
Common questions
What is lymphoma in dogs?
Lymphoma is a cancer of the lymphocytes, a type of white blood cell. It's one of the most common cancers in dogs.
What are the signs of lymphoma?
Common signs include: firm, swollen lymph nodes under the jaw, in front of the shoulders or behind the knees, low energy, weight loss, drinking more.
How do vets diagnose lymphoma?
A needle sample of a lymph node usually diagnoses it. Bloodwork, X-rays, ultrasound and special lab tests help with staging.
How is lymphoma treated?
Chemotherapy is the main treatment, and most dogs handle it much better than people do. Prednisone alone is a comfort-focused option.
How much does lymphoma cost to treat?
Diagnosis (exam and tests): $500–$1,000; Treatment: $3,000–$10,000; Lymphoma chemotherapy, dog (CareCredit): $5,254. Costs vary with severity, tests, your pet's size and where you live.
Related
This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.