Steroids & immune Dogs

Pentoxifylline for dogs

Treats certain immune skin diseases and blood vessel inflammation such as ear-tip vasculitis. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerPentoxifylline is a prescription medicine for dogs. It improves blood flow and dampens inflammation. The most common side effects: vomiting, diarrhea, low appetite, excitement and restlessness.

Key facts

Generic namePentoxifylline
Common brand namesTrental
Used inDogs
TypeSteroids & immune
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Treats certain immune skin diseases and blood vessel inflammation such as ear-tip vasculitis. [1]

How it works

It improves blood flow and dampens inflammation. [1]

Side effects and cautions

Common side effects: Vomiting, diarrhea, low appetite, excitement and restlessness. [1]

Use with care: Not for pets with bleeding in the brain or eye. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Pentoxifylline FAQ

What is Pentoxifylline used for in dogs?

Treats certain immune skin diseases and blood vessel inflammation such as ear-tip vasculitis.

What are the side effects of Pentoxifylline?

Vomiting, diarrhea, low appetite, excitement and restlessness.

Does Pentoxifylline need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Pentoxifylline should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Pentoxifylline (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs