Eye & skin Dogs & Cats

Tacrolimus for dogs and cats

An ointment that controls inflammation and itch from allergies or immune disease. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerTacrolimus (tacrolimus (topical)) is a prescription medicine for dogs and cats. Like cyclosporine, it quiets local immune cells. The most common side effects: mild irritation or redness where applied.

Key facts

Generic nameTacrolimus (topical)
Common brand namesProtopic
Used inDogs & Cats
TypeEye & skin
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

An ointment that controls inflammation and itch from allergies or immune disease. [1]

How it works

Like cyclosporine, it quiets local immune cells. [1]

Side effects and cautions

Common side effects: Mild irritation or redness where applied. [1]

Use with care: Wear gloves. Use caution with other immune-suppressing drugs. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Tacrolimus FAQ

What is Tacrolimus used for in dogs and cats?

An ointment that controls inflammation and itch from allergies or immune disease.

What are the side effects of Tacrolimus?

Mild irritation or redness where applied.

Does Tacrolimus need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Tacrolimus should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

Related medications

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Tacrolimus (topical) (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs