Meloxicam vs Robenacoxib: what's the difference?
How Meloxicam and Robenacoxib compare: what each is for, how it works, side effects and cost, side by side.
Last updated: October 2026 · 3 sources · see sources
Side by side
| Meloxicam | Robenacoxib | |
|---|---|---|
| Generic name | Meloxicam | Robenacoxib |
| Brand names | Metacam, Loxicom, OroCAM | Onsior |
| For | Dogs and cats | Dogs and cats |
| Prescription | Prescription | Prescription |
| Used for | Relieves pain, inflammation and fever. It is labeled for osteoarthritis in dogs and for pain after surgery. [1] | Controls pain and inflammation after surgery in dogs and cats. [2] |
| How it works | An NSAID that lowers prostaglandins, which drive pain and swelling. [1] | A COX-2 selective NSAID that is used for short courses. [2] |
| Common side effects | Stomach upset is most common: vomiting, soft stool and low appetite. Rarely, kidney or liver problems. [1] | Low appetite, tiredness, vomiting and diarrhea. Kidney problems and bleeding at the incision site are possible. [2] |
| Use with care | Cats are more sensitive to NSAIDs, so follow your vet's plan exactly. Not for pets with kidney or liver disease or bloody vomit or stool. Never combine with another NSAID or a steroid. [1] | Not for pets with stomach ulcers, pets that are pregnant or nursing, or pets under four months old. [2] |
| Typical price | Meloxicam for a dog, at a pharmacy: $4–$15 a month [3] | No reliable published price |
| Full guide | Meloxicam (Metacam) guide | Robenacoxib (Onsior) guide |
Key differences
On the basics they are alike: same kind of animal, same way to get them. The differences are in how they work and what else they cover, shown in the table above.
Which one is right for my pet?
That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.
Switching from Meloxicam to Robenacoxib is common, but do it only with your vet's plan.
Common questions
What is the difference between Meloxicam and Robenacoxib?
Both are NSAIDs used in dogs and cats. Onsior is COX-2 selective and is used for short courses after surgery.
Is Meloxicam better than Robenacoxib?
Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.
Can my pet take Meloxicam and Robenacoxib together?
Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.
Do Meloxicam and Robenacoxib need a prescription?
Meloxicam: Yes. It needs a prescription from a veterinarian. Robenacoxib: Yes. It needs a prescription from a veterinarian.
How much do Meloxicam and Robenacoxib cost?
Meloxicam: Meloxicam for a dog, at a pharmacy $4–$15 a month. Robenacoxib: no reliable published price. Prices vary by pet size, pharmacy and clinic.
Related
This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.