NexGard vs Bravecto: what's the difference?
How NexGard and Bravecto compare: what each is for, how it works, side effects and cost, side by side.
Last updated: October 2026 · 2 sources · see sources
Side by side
| NexGard | Bravecto | |
|---|---|---|
| Generic name | Afoxolaner | Fluralaner |
| Brand names | NexGard, NexGard Plus, NexGard Spectra | Bravecto, Bravecto Plus |
| For | Dogs | Dogs and cats |
| Prescription | Prescription | Prescription |
| Used for | A monthly chew that kills fleas and ticks in dogs and helps prevent Lyme disease. [1] | Kills fleas and ticks for up to 12 weeks in dogs and cats. Sometimes used for mange and ear mites. [2] |
| How it works | It spreads through the dog's body, and fleas and ticks die after biting. [1] | After it is given, it spreads through the body. Fleas and ticks are exposed when they bite and are killed. [2] |
| Common side effects | Very few in most dogs. Vomiting and diarrhea can happen. [1] | Vomiting, diarrhea, low appetite and flaky skin. [2] |
| Use with care | An isoxazoline: the FDA has warned of possible tremors, wobbliness and seizures. Not for puppies under 8 weeks or 4 pounds unless your vet says so. [1] | It belongs to the isoxazoline class, which the FDA says has been linked to tremors, wobbliness and seizures in some pets. Tell your vet if your pet has ever had a seizure. [2] |
| Full guide | NexGard guide | Bravecto guide |
Key differences
- They aren't made for the same animals: NexGard is for dogs; Bravecto is for dogs and cats.
Which one is right for my pet?
That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.
Switching from NexGard to Bravecto is common, but do it only with your vet's plan.
Common questions
What is the difference between NexGard and Bravecto?
Both kill fleas and ticks. NexGard is a monthly chew for dogs; Bravecto lasts up to 12 weeks and comes in forms for dogs and cats.
Is NexGard better than Bravecto?
Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.
Can my pet take NexGard and Bravecto together?
Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.
Do NexGard and Bravecto need a prescription?
NexGard: Yes. It needs a prescription from a veterinarian. Bravecto: Yes. It needs a prescription from a veterinarian.
Related
This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.