Polycystic kidney disease (PKD) in cats
PKD is an inherited disease where fluid-filled cysts grow in the kidneys. Persians and related breeds are most often affected.
Last updated: October 2026 · 2 sources · see sources
Signs to watch for
- Often none early
- Later the same signs as kidney disease: thirst, weight loss, poor appetite
Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.
How vets diagnose it
Ultrasound finds the cysts. A DNA test is available for some breeds. [2]
How it's treated
There's no cure. Management follows chronic kidney disease care. [2]
Medicines your vet may mention: Amlodipine, Cerenia. We don't list doses; your vet will decide what fits your pet.
What it costs to diagnose and manage
| Item | Typical US price | Src |
|---|---|---|
| Diagnosis (exam and tests) | $200–$500 | [1] |
| Ongoing treatment, per month | $200–$500 | [1] |
| Ongoing treatment over a year (monthly range × 12) | $2,400–$6,000 | [1] |
These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.
Outlook
Progression varies a lot between cats. [2]
Common questions
What is polycystic kidney disease (PKD) in cats?
PKD is an inherited disease where fluid-filled cysts grow in the kidneys. Persians and related breeds are most often affected.
What are the signs of polycystic kidney disease (PKD)?
Common signs include: often none early, later the same signs as kidney disease: thirst, weight loss, poor appetite.
How do vets diagnose polycystic kidney disease (PKD)?
Ultrasound finds the cysts. A DNA test is available for some breeds.
How is polycystic kidney disease (PKD) treated?
There's no cure. Management follows chronic kidney disease care.
How much does polycystic kidney disease (PKD) cost to treat?
Diagnosis (exam and tests): $200–$500; Ongoing treatment, per month: $200–$500; Ongoing treatment over a year (monthly range × 12): $2,400–$6,000. Costs vary with severity, tests, your pet's size and where you live.
Related
This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.