Condition guide Dogs

Pyometra in dogs

Pyometra is a serious infection of the uterus in unspayed females, usually a few weeks after a heat cycle.

Last updated: October 2026 · 3 sources · see sources

Quick answerPyometra is a serious infection of the uterus in unspayed females, usually a few weeks after a heat cycle. Cost: diagnosis typically runs $300–$600; treatment: $1,500–$4,000 [1].

Signs to watch for

[2][3]

Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.

How vets diagnose it

Ultrasound or X-rays show an enlarged uterus. Bloodwork checks how sick the dog is. [2][3]

How it's treated

Emergency spay surgery is the usual treatment, with fluids and antibiotics. [2][3]

Medicines your vet may mention: Clavamox. We don't list doses; your vet will decide what fits your pet.

What it costs to diagnose and manage

Typical US costs
ItemTypical US priceSrc
Diagnosis (exam and tests)$300–$600[1]
Treatment$1,500–$4,000[1]

These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.

Outlook

Most dogs recover well after surgery. Spaying prevents it. [2][3]

Common questions

What is pyometra in dogs?

Pyometra is a serious infection of the uterus in unspayed females, usually a few weeks after a heat cycle.

What are the signs of pyometra?

Common signs include: drinking and peeing more, vaginal discharge (if open), lethargy, vomiting, swollen belly.

How do vets diagnose pyometra?

Ultrasound or X-rays show an enlarged uterus. Bloodwork checks how sick the dog is.

How is pyometra treated?

Emergency spay surgery is the usual treatment, with fluids and antibiotics.

How much does pyometra cost to treat?

Diagnosis (exam and tests): $300–$600; Treatment: $1,500–$4,000. Costs vary with severity, tests, your pet's size and where you live.

This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (3) — tap to show
  1. RealVetCost – Pyometra in dogs: symptoms, treatment & costs
  2. Merck Veterinary Manual (pet owner version) – Reproductive disorders of female dogs
  3. American College of Veterinary Surgeons (ACVS) – Pyometra