Carprofen vs Firocoxib: what's the difference?
How Carprofen and Firocoxib compare: what each is for, how it works, side effects and cost, side by side.
Last updated: October 2026 · 4 sources · see sources
Side by side
| Carprofen | Firocoxib | |
|---|---|---|
| Generic name | Carprofen | Firocoxib |
| Brand names | Rimadyl, Novox, Vetprofen, Carprieve, Rovera | Previcox |
| For | Dogs | Dogs |
| Prescription | Prescription | Prescription |
| Used for | Treats pain and inflammation in dogs, such as arthritis pain and pain after surgery. [1] | Treats pain and inflammation from arthritis, surgery or injury in dogs. [2] |
| How it works | It is an NSAID. It blocks enzymes that make prostaglandins, the chemicals that cause pain and swelling. [1] | A COX-2 selective NSAID. [2] |
| Common side effects | Vomiting, low appetite, diarrhea, constipation and tiredness. Rarely, liver, kidney or stomach damage. [1] | Vomiting and low appetite. Serious stomach, kidney or liver problems are rare but possible. [2] |
| Use with care | Never combine with other NSAIDs or steroids. Not for dogs with bleeding disorders. Stop and call your vet for black or bloody stool, yellow gums or eyes, or changes in drinking or urination. Never give human pain relievers instead. [1] | Not for dogs under seven months old or dogs on a steroid or another NSAID. [2] |
| Typical price | Carprofen or Rimadyl: $12–$50 a month [3] Rimadyl, typical owner bill (103 bills): $15–$50 [4] | No reliable published price |
| Full guide | Carprofen (Rimadyl) guide | Firocoxib (Previcox) guide |
Key differences
On the basics they are alike: same kind of animal, same way to get them. The differences are in how they work and what else they cover, shown in the table above.
Which one is right for my pet?
That is a call for your vet. They weigh your pet's age, weight, other health problems, other medicines and what you can realistically give at home.
Switching from Carprofen to Firocoxib is common, but do it only with your vet's plan.
Common questions
What is the difference between Carprofen and Firocoxib?
Both are NSAIDs for arthritis and surgery pain in dogs. Firocoxib is COX-2 selective.
Is Carprofen better than Firocoxib?
Neither is better for every pet. Your vet chooses based on your pet's species, age, health history, other medicines and what you can manage at home.
Can my pet take Carprofen and Firocoxib together?
Only if your vet says so. Some medicines in the same family should not be combined, and others are often used together. Always check before adding or switching.
Do Carprofen and Firocoxib need a prescription?
Carprofen: Yes. It needs a prescription from a veterinarian. Firocoxib: Yes. It needs a prescription from a veterinarian.
How much do Carprofen and Firocoxib cost?
Carprofen: Carprofen or Rimadyl $12–$50 a month. Firocoxib: no reliable published price. Prices vary by pet size, pharmacy and clinic.
Related
This page is general information for planning, not veterinary advice. Talk to your vet about your own pet.