Addison's disease in dogs
Addison's disease (hypoadrenocorticism) is the opposite of Cushing's: the adrenal glands don't make enough cortisol and often aldosterone. It's sometimes called 'the great pretender' because the signs are vague.
Last updated: October 2026 · 2 sources · see sources
Signs to watch for
- Off-and-on vomiting or diarrhea
- Low energy
- Poor appetite
- Weight loss
- Shaking
- Sudden collapse in a crisis
Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.
How vets diagnose it
Bloodwork may show telltale electrolyte changes. An ACTH stimulation test confirms the diagnosis. [2]
How it's treated
Dogs in crisis need emergency IV fluids and hospital care. Long-term, most dogs get a hormone injection about monthly (DOCP) and/or daily pills, with regular bloodwork. [2]
Medicines your vet may mention: Zycortal / Percorten-V (DOCP), Fludrocortisone, Prednisone & Prednisolone. We don't list doses; your vet will decide what fits your pet.
What it costs to diagnose and manage
| Item | Typical US price | Src |
|---|---|---|
| Diagnosis (exam and tests) | $300–$600 | [1] |
| Ongoing treatment, per month | $50–$100 | [1] |
| Ongoing treatment over a year (monthly range × 12) | $600–$1,200 | [1] |
These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.
Outlook
Once stable, most dogs with Addison's live normal, active lives with lifelong treatment. [2]
Common questions
What is Addison's disease in dogs?
Addison's disease (hypoadrenocorticism) is the opposite of Cushing's: the adrenal glands don't make enough cortisol and often aldosterone. It's sometimes called 'the great pretender' because the signs are vague.
What are the signs of Addison's disease?
Common signs include: off-and-on vomiting or diarrhea, low energy, poor appetite, weight loss, shaking, sudden collapse in a crisis.
How do vets diagnose Addison's disease?
Bloodwork may show telltale electrolyte changes. An ACTH stimulation test confirms the diagnosis.
How is Addison's disease treated?
Dogs in crisis need emergency IV fluids and hospital care. Long-term, most dogs get a hormone injection about monthly (DOCP) and/or daily pills, with regular bloodwork.
How much does Addison's disease cost to treat?
Diagnosis (exam and tests): $300–$600; Ongoing treatment, per month: $50–$100; Ongoing treatment over a year (monthly range × 12): $600–$1,200. Costs vary with severity, tests, your pet's size and where you live.
Related
This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.