Condition guide Dogs

Liver disease in dogs

Liver disease covers many problems, from inflammation (hepatitis) and copper storage disease to shunts and tumors. The liver can often recover well if the cause is found.

Last updated: October 2026 · 2 sources · see sources

Quick answerLiver disease covers many problems, from inflammation (hepatitis) and copper storage disease to shunts and tumors. Cost: diagnosis typically runs $300–$800; treatment: $100–$6,000 [1].

Signs to watch for

[2]

Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.

How vets diagnose it

Bloodwork shows raised liver enzymes. Bile acid tests, ultrasound and sometimes a liver biopsy find the cause. [2]

How it's treated

Treatment depends on the cause and may include special diets, liver-support medicines like ursodiol or SAMe, antibiotics, or surgery for shunts and tumors. [2]

Medicines your vet may mention: Ursodiol. We don't list doses; your vet will decide what fits your pet.

What it costs to diagnose and manage

Typical US costs
ItemTypical US priceSrc
Diagnosis (exam and tests)$300–$800[1]
Treatment$100–$6,000[1]

These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.

Outlook

Outlook varies widely, so ask your vet what to expect for your dog's specific diagnosis. [2]

Common questions

What is liver disease in dogs?

Liver disease covers many problems, from inflammation (hepatitis) and copper storage disease to shunts and tumors. The liver can often recover well if the cause is found.

What are the signs of liver disease?

Common signs include: poor appetite, vomiting, weight loss, yellow gums or eyes (jaundice), drinking more, swollen belly, confusion.

How do vets diagnose liver disease?

Bloodwork shows raised liver enzymes. Bile acid tests, ultrasound and sometimes a liver biopsy find the cause.

How is liver disease treated?

Treatment depends on the cause and may include special diets, liver-support medicines like ursodiol or SAMe, antibiotics, or surgery for shunts and tumors.

How much does liver disease cost to treat?

Diagnosis (exam and tests): $300–$800; Treatment: $100–$6,000. Costs vary with severity, tests, your pet's size and where you live.

This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. RealVetCost – Liver Disease in dogs: symptoms, treatment & costs
  2. Merck Veterinary Manual (pet owner version) – Disorders of the liver and gallbladder