Stomach & digestion Dogs & Cats

Ursodiol for dogs and cats

Treats gallbladder and bile-related liver disease such as gallbladder sludge and chronic liver inflammation. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerUrsodiol is a prescription medicine for dogs and cats. It thins bile and protects liver cells from harsh bile acids. The most common side effects: diarrhea and mild discomfort.

Key facts

Generic nameUrsodiol
Common brand namesActigall, Urso
Used inDogs & Cats
TypeStomach & digestion
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Treats gallbladder and bile-related liver disease such as gallbladder sludge and chronic liver inflammation. [1]

How it works

It thins bile and protects liver cells from harsh bile acids. [1]

Side effects and cautions

Common side effects: Diarrhea and mild discomfort. [1]

Use with care: Use caution if gallstones could block the bile duct. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Ursodiol FAQ

What is Ursodiol used for in dogs and cats?

Treats gallbladder and bile-related liver disease such as gallbladder sludge and chronic liver inflammation.

What are the side effects of Ursodiol?

Diarrhea and mild discomfort.

Does Ursodiol need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Ursodiol should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Ursodiol (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs