Pain & arthritis Dogs

Adequan for dogs

Treats non-infectious and injury-related arthritis in dogs. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerAdequan (polysulfated glycosaminoglycan) is a prescription, given at the clinic medicine for dogs. An injectable joint drug that helps slow cartilage breakdown and reduce joint inflammation. The most common side effects: rare.

Key facts

Generic namePolysulfated glycosaminoglycan
Common brand namesAdequan Canine
Used inDogs
TypePain & arthritis
Prescription?Prescription, given at the clinic
Typical US priceNot listed (no reliable public source)

What it's used for

Treats non-infectious and injury-related arthritis in dogs. [1]

How it works

An injectable joint drug that helps slow cartilage breakdown and reduce joint inflammation. [1]

Side effects and cautions

Common side effects: Rare. Brief pain at the injection site, short-lived vomiting or diarrhea. [1]

Use with care: Not for pets with bleeding disorders. Use caution with kidney or liver disease. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Adequan FAQ

What is Adequan used for in dogs?

Treats non-infectious and injury-related arthritis in dogs.

What are the side effects of Adequan?

Rare. Brief pain at the injection site, short-lived vomiting or diarrhea.

Does Adequan need a prescription?

Yes. It's prescription-only and is usually given at the vet clinic.

How much Adequan should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Polysulfated glycosaminoglycan (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs