Antibiotics Dogs & Cats

Cephalexin for dogs and cats

Treats skin infections (pyoderma) in dogs. Vets also use it in cats and for some urinary infections. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerCephalexin is a prescription medicine for dogs and cats. A cephalosporin antibiotic that damages bacterial cell walls. The most common side effects: vomiting, diarrhea and low appetite.

Key facts

Generic nameCephalexin
Common brand namesRilexine, Keflex
Used inDogs & Cats
TypeAntibiotics
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Treats skin infections (pyoderma) in dogs. Vets also use it in cats and for some urinary infections. [1]

How it works

A cephalosporin antibiotic that damages bacterial cell walls. [1]

Side effects and cautions

Common side effects: Vomiting, diarrhea and low appetite. [1]

Use with care: Not for pets allergic to cephalosporins; use caution with penicillin allergy. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Cephalexin FAQ

What is Cephalexin used for in dogs and cats?

Treats skin infections (pyoderma) in dogs. Vets also use it in cats and for some urinary infections.

What are the side effects of Cephalexin?

Vomiting, diarrhea and low appetite.

Does Cephalexin need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Cephalexin should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

Related medications

Related cost guides

This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Cephalexin (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs