Flea, tick & heartworm Dogs & Cats

Frontline for dogs and cats

A topical that kills fleas, ticks and chewing lice in dogs and cats. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerFrontline (fipronil) is a over the counter medicine for dogs and cats. It disrupts the nervous system of insects and ticks. The most common side effects: uncommon.

Key facts

Generic nameFipronil
Common brand namesFrontline, PetArmor, Parastar
Used inDogs & Cats
TypeFlea, tick & heartworm
Prescription?Over the counter (ask your vet first)
Typical US priceNot listed (no reliable public source)

What it's used for

A topical that kills fleas, ticks and chewing lice in dogs and cats. [1]

How it works

It disrupts the nervous system of insects and ticks. [1]

Side effects and cautions

Common side effects: Uncommon. Temporary irritation at the application spot. [1]

Use with care: Not for puppies or kittens under 8 weeks, or for rabbits. Use the right product for your pet's species and weight. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Frontline FAQ

What is Frontline used for in dogs and cats?

A topical that kills fleas, ticks and chewing lice in dogs and cats.

What are the side effects of Frontline?

Uncommon. Temporary irritation at the application spot.

Does Frontline need a prescription?

Many forms are sold without a prescription. Still, check with your vet first. Pet doses and safe products are not the same as for people.

How much Frontline should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Fipronil (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs