Stomach & digestion Dogs & Cats

Lactulose for dogs and cats

Softens stool for constipation and lowers blood ammonia in liver disease. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerLactulose is a prescription medicine for dogs and cats. A sugar the body can't digest, which pulls water into the colon and traps ammonia. The most common side effects: diarrhea, bloating, gas and cramps.

Key facts

Generic nameLactulose
Common brand namesEnulose, Kristalose
Used inDogs & Cats
TypeStomach & digestion
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Softens stool for constipation and lowers blood ammonia in liver disease. [1]

How it works

A sugar the body can't digest, which pulls water into the colon and traps ammonia. [1]

Side effects and cautions

Common side effects: Diarrhea, bloating, gas and cramps. [1]

Use with care: Not for pets with a gut blockage. Use caution in diabetic pets. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Lactulose FAQ

What is Lactulose used for in dogs and cats?

Softens stool for constipation and lowers blood ammonia in liver disease.

What are the side effects of Lactulose?

Diarrhea, bloating, gas and cramps.

Does Lactulose need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Lactulose should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Lactulose (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs