Stomach & digestion Dogs & Cats

Omeprazole (Prilosec) for dogs and cats

Treats stomach and upper gut ulcers and helps prevent ulcers from drugs like NSAIDs. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerOmeprazole is a over the counter medicine for dogs and cats. A proton-pump inhibitor: it lowers acid more strongly than famotidine. The most common side effects: vomiting, low appetite, gas and diarrhea.

Key facts

Generic nameOmeprazole
Common brand namesPrilosec, Gastrogard
Used inDogs & Cats
TypeStomach & digestion
Prescription?Over the counter (ask your vet first)
Typical US priceNot listed (no reliable public source)

What it's used for

Treats stomach and upper gut ulcers and helps prevent ulcers from drugs like NSAIDs. [1]

How it works

A proton-pump inhibitor: it lowers acid more strongly than famotidine. [1]

Side effects and cautions

Common side effects: Vomiting, low appetite, gas and diarrhea. [1]

Use with care: Use caution in pets with liver or kidney disease. Ask your vet before giving a human product. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Omeprazole FAQ

What is Omeprazole used for in dogs and cats?

Treats stomach and upper gut ulcers and helps prevent ulcers from drugs like NSAIDs.

What are the side effects of Omeprazole?

Vomiting, low appetite, gas and diarrhea.

Does Omeprazole need a prescription?

Many forms are sold without a prescription. Still, check with your vet first. Pet doses and safe products are not the same as for people.

How much Omeprazole should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Omeprazole (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs