Eye & skin Dogs

Optimmune (Cyclosporine eye ointment) for dogs

Treats dry eye (keratoconjunctivitis sicca) and other immune-related eye inflammation. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerOptimmune (cyclosporine (ophthalmic)) is a prescription medicine for dogs. It calms the immune attack on tear glands so they make more tears. The most common side effects: mild burning, redness or eyelid spasms.

Key facts

Generic nameCyclosporine (ophthalmic)
Common brand namesOptimmune, Restasis
Used inDogs
TypeEye & skin
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Treats dry eye (keratoconjunctivitis sicca) and other immune-related eye inflammation. [1]

How it works

It calms the immune attack on tear glands so they make more tears. [1]

Side effects and cautions

Common side effects: Mild burning, redness or eyelid spasms. [1]

Use with care: Not for eyes with viral or fungal infections. It is usually a long-term treatment. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Optimmune FAQ

What is Optimmune used for in dogs?

Treats dry eye (keratoconjunctivitis sicca) and other immune-related eye inflammation.

What are the side effects of Optimmune?

Mild burning, redness or eyelid spasms.

Does Optimmune need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Optimmune should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Cyclosporine (ophthalmic) (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs