Osteosarcoma (bone cancer) in dogs
Osteosarcoma is an aggressive bone cancer, most common in the legs of large and giant breeds.
Last updated: October 2026 · 3 sources · see sources
Signs to watch for
- Limping that doesn't go away
- A firm swelling on a leg
- Pain
- Sometimes a sudden fracture
Trouble breathing, collapse, repeated vomiting, not peeing, or a seizure that lasts more than a few minutes needs a vet right away. See when to see a vet.
How vets diagnose it
X-rays of the leg often suggest it, and a biopsy or needle sample confirms it. Chest X-rays or CT check for spread. [2][3]
How it's treated
Common options are amputation with chemotherapy, limb-sparing surgery, or radiation for pain relief. [2][3]
Medicines your vet may mention: Carprofen (Rimadyl), Gabapentin, Amantadine. We don't list doses; your vet will decide what fits your pet.
What it costs to diagnose and manage
| Item | Typical US price | Src |
|---|---|---|
| Diagnosis (exam and tests) | $500–$1,500 | [1] |
| Treatment | $5,000–$13,000 | [1] |
These are typical US ranges from the sources listed. Your pet's costs depend on how severe things are, the tests your vet recommends, your pet's size and where you live. Ask your vet for a written estimate.
Outlook
Treatment can give many good months. Pain control is a priority whatever plan you choose. [2][3]
Common questions
What is osteosarcoma (bone cancer) in dogs?
Osteosarcoma is an aggressive bone cancer, most common in the legs of large and giant breeds.
What are the signs of osteosarcoma (bone cancer)?
Common signs include: limping that doesn't go away, a firm swelling on a leg, pain, sometimes a sudden fracture.
How do vets diagnose osteosarcoma (bone cancer)?
X-rays of the leg often suggest it, and a biopsy or needle sample confirms it. Chest X-rays or CT check for spread.
How is osteosarcoma (bone cancer) treated?
Common options are amputation with chemotherapy, limb-sparing surgery, or radiation for pain relief.
How much does osteosarcoma (bone cancer) cost to treat?
Diagnosis (exam and tests): $500–$1,500; Treatment: $5,000–$13,000. Costs vary with severity, tests, your pet's size and where you live.
Related
This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.