Flea, tick & heartworm Dogs & Cats

Ivermectin (Heartgard) for dogs and cats

Mainly a monthly heartworm preventive. Vets also use it for mites and some worms. [1]

Last reviewed: October 2026 · 4 sources · see sources

Quick answerIvermectin is a prescription medicine for dogs and cats. At preventive doses it kills young heartworm larvae before they can grow into adult worms. The most common side effects: well tolerated at heartworm-prevention doses.

Key facts

Generic nameIvermectin
Common brand namesHeartgard, Heartgard Plus, Tri-Heart
Used inDogs & Cats
TypeFlea, tick & heartworm
Prescription?Prescription
Typical US price$6–$18 a dose [3]

What it's used for

Mainly a monthly heartworm preventive. Vets also use it for mites and some worms. [1]

How it works

At preventive doses it kills young heartworm larvae before they can grow into adult worms. [1]

Side effects and cautions

Common side effects: Well tolerated at heartworm-prevention doses. Higher doses can cause wobbliness, tremors, dilated pupils and drooling. [1]

Use with care: Collies, sheepdogs and related breeds can be very sensitive at high doses (MDR1 gene). Dogs need a negative heartworm test first. [1] [2]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [4].

What it costs

Prices come from public owner-bill reports and vary by clinic, pharmacy, pet size and dose.

Ivermectin FAQ

What is Ivermectin used for in dogs and cats?

Mainly a monthly heartworm preventive. Vets also use it for mites and some worms.

What are the side effects of Ivermectin?

Well tolerated at heartworm-prevention doses. Higher doses can cause wobbliness, tremors, dilated pupils and drooling.

Does Ivermectin need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Ivermectin should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

Related medications

Related cost guides

This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (4) — tap to show
  1. VCA Animal Hospitals – Ivermectin (veterinary drug handout)
  2. FDA – Keep worms out of your pet's heart
  3. VetReceipt – Dog heartworm treatment cost (owner bills)
  4. FDA – Frequently asked questions about animal drugs