Anxiety & behavior Dogs & Cats

Acepromazine for dogs and cats

A sedative used before anesthesia and for restraint. [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerAcepromazine is a prescription medicine for dogs and cats. A phenothiazine tranquilizer that dampens dopamine signals. The most common side effects: low blood pressure is the most important side effect.

Key facts

Generic nameAcepromazine
Common brand namesPromAce
Used inDogs & Cats
TypeAnxiety & behavior
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

A sedative used before anesthesia and for restraint. [1]

How it works

A phenothiazine tranquilizer that dampens dopamine signals. [1]

Side effects and cautions

Common side effects: Low blood pressure is the most important side effect. Sometimes aggression or hyperactivity. [1]

Use with care: Not for pets with heart disease, low blood pressure or severe dehydration. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Acepromazine FAQ

What is Acepromazine used for in dogs and cats?

A sedative used before anesthesia and for restraint.

What are the side effects of Acepromazine?

Low blood pressure is the most important side effect. Sometimes aggression or hyperactivity.

Does Acepromazine need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Acepromazine should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

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This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Acepromazine (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs