Anxiety & behavior Dogs

Anipryl (Selegiline) for dogs

Treats signs of canine cognitive dysfunction (dog 'dementia'). [1]

Last reviewed: October 2026 · 2 sources · see sources

Quick answerAnipryl (selegiline) is a prescription medicine for dogs. An MAOI that raises dopamine in the brain. The most common side effects: vomiting, diarrhea, restlessness, confusion and tiredness.

Key facts

Generic nameSelegiline
Common brand namesAnipryl
Used inDogs
TypeAnxiety & behavior
Prescription?Prescription
Typical US priceNot listed (no reliable public source)

What it's used for

Treats signs of canine cognitive dysfunction (dog 'dementia'). [1]

How it works

An MAOI that raises dopamine in the brain. [1]

Side effects and cautions

Common side effects: Vomiting, diarrhea, restlessness, confusion and tiredness. [1]

Use with care: Never combine with tramadol, SSRIs, tricyclics or amitraz tick collars. [1]

Call your vet right away if your pet has trouble breathing, facial swelling, hives, collapse, or any side effect that is severe or getting worse.

About dosingDosing is your vet's call. We don't list doses because the right amount depends on your pet's weight, age, health and other medicines. Don't change a dose or stop a medicine without asking your vet, and never give a pet medicine meant for people unless your vet tells you to [2].

What it costs

We don't list a price for this one because we couldn't find a reliable public source. Ask your vet or pharmacy for a quote; prices depend on your pet's size, the dose and where you fill it.

Anipryl FAQ

What is Anipryl used for in dogs?

Treats signs of canine cognitive dysfunction (dog 'dementia').

What are the side effects of Anipryl?

Vomiting, diarrhea, restlessness, confusion and tiredness.

Does Anipryl need a prescription?

Yes. It needs a prescription from a veterinarian.

How much Anipryl should I give my pet?

Only your veterinarian can tell you. The right dose depends on your pet's weight, health and other medicines, so we don't list doses. Never give a pet a medicine prescribed for a person or another animal without asking your vet.

Related medications

Related cost guides

This page is general information for pet owners, not veterinary advice. Talk to your vet about your own pet.

Sources (2) — tap to show
  1. VCA Animal Hospitals – Selegiline (veterinary drug handout)
  2. FDA – Frequently asked questions about animal drugs